Background: Haemorrhoidal disease, a most common anorectal disorder, affecting, almost 50% of population. The present study was conducted to assess clinical outcomes of Ligasure vessel sealer haemorrhoidectomy in patients with symptomatic haemorrhoids. Materials & Methods: Present study was conducted in between November 2015 to September 2016 at Govt. Medical College & Hospital, Kilpauk, Chennai. 62 patients with symptomatic haemorrhoids (Grade II to Grade IV), age ranged from 22 – 70 years of both genders admitted to Department of General Surgery underwent Ligasure vessel sealer haemorrhoidectomy. They were asked to grade the severity of pain on Visual Analogue Scale (0-10) (VAS) on the next morning of surgery (day 1), the next day (day 3) and after 1 week of follow up (day 7). Results: Out of 62 patients, males were 71% and females were 29%.The maximum age distribution of patient, presenting with haemorrhoids, was in the age group of 40- 50 years -35 patients (56.4%) common for male and females. The maximum percentage of patients presented with Grade 3 haemorrhoids i.e. 54.8% (34 patients). The mean age group for prolapsed Grade 2 haemorrhoids was 29 years, for Grade 3 haemorrhoids was 43 years and for Grade 4 haemorrhoids was 56 years, among both female and male groups. The preoperative assessment of continence was done through Wexner incontinence score and was ranged from 1 to 2, thus all patients were found completely continent before surgery. The duration of surgery ranged from 15- 25 minutes, with 35 patients (56.4%) completed surgery within 20-25 minutes and 27 patients (43.5%) completed surgery within 15-20 minutes. Thus, the mean operative time of the study calculated was found to be 20.6 minutes. There was intraoperative blood loss ranging from 5 ml to 25 ml with 66% of patient had a blood loss of 16- 20 ml followed by 26 % of the patient had a blood loss of 21- 25 ml. There were no major per operative complications. The difference was significant (P< 0.05).Post-operative pain evaluation was done through visual analogue score (VAS) and found that maximum number of patients i.e. 51 patients (82%) had mild pain at postoperative day 1 (POD 1- VAS-3), with concurrent reduction in symptoms of pain at 3rd postoperative day (POD 3- VAS-1) and at 1st week (VAS-0). Conclusion: Ligasure vessel sealer haemorrhoidectomy showed a promising results of less postoperative pain and decreased rate of complications in our study and should be considered as an alternative to conventional haemorrhoidectomy in symptomatic patients with grade II, grade III and grade IV haemorrhoids.