Aim:To assess the disparity in success rates of dental implants between individuals who smoke and those who do not smoke. Material and methods: This retrospective investigation includes a cohort of 120 patients who had dental implant operations throughout the study period. The patient selection criteria were individuals who had received dental implant therapy for one or more missing teeth and were at least eighteen years of age. The study sample included 60 smokers and 60 non-smokers. This was accomplished via meticulous examination of patient records and smoking history information housed in the center's database. Results: The study found that there were significant disparities in implant survival rates between smokers and non-smokers. The implant survival rate was much higher in the non-smoking group, with a rate of 98.33%, compared to the smoking group, which had a rate of 91.67%.The prevalence of peri-implantitis was 26.67% in the smoking group, compared to just 11.67% in the non-smoking group. This study highlights the heightened susceptibility of smokers to develop inflammatory complications related to implants. Smokers had an average marginal bone loss of 2.6 mm, but non-smokers showed a much lower average of 1.2 mm. The significant disparity in bone loss suggests that those who smoke have inferior bone remodeling and maintenance in the vicinity of their implants. Conclusion: The finding of this study underscores the substantial detrimental impact of smoking on the outcomes of dental implant procedures. Smoking adversely affects osseointegration and the longevity of implants, as shown by poorer rates of implant survival, a higher occurrence of peri-implantitis, and increased marginal bone loss in those who smoke. These findings emphasize the need of personalized treatment strategies and rigorous postoperative care guidelines, particularly for those who smoke.