Introduction: Soft tissue is defined as nonepithelial extraskeletal tissue of the body. Soft tissue tumors are a heterogeneous group of tumors and the pathogenesis most of which is not known. They are diverse neoplasms with overlapping clinical and radiological features so histopathology is needed for appropriate diagnosis. Objectives: The main objectives of the present prospective study are to analyze histopathological patterns of soft tissue tumors to study the frequency of distribution of soft tissue tumors in terms of age, gender and sites in the body. Materials and Methods: This is a prospective study carried out specimens of soft tissue tumors which includes biopsy as well as surgically excised specimens were received in histopathology department of GMERS Medical College, Gandhinagar, Gujarat during 6 months study period from 1st September, 2023 to 29th February, 2024. The formalin fixed specimens are processed and examined under the microscope. Result: Out of 50 cases 88% are benign and 12% are malignant tumors and majority were lipomatous tumor (64%) followed by tumor of uncertain differentiation (10%). Incidence of cases found more in male with male to female ratio of 1.5:1. Most common age group was 31-40 years both in male and female, comprising total 17 (34%) cases followed 51-60 years comprising 10 (20%) cases. Most common site observed was thigh comprising 9 (18%) cases followed by back comprising 7 (14%) cases. Conclusion: Soft tissue tumors pose diagnostic challenges due to confounding morphological characteristics. Hence histopathological examination is gold standard tool soft tissue tumors’ diagnosis.