Background &Objectives:Diabetes mellitus is the collective term for disorders affecting glucose homeostasis. The pancreas is situated in the retroperitoneum within the anterior pararenal fascial space, positioned anteriorly to the aorta and inferior vena cava. Specifically, the pancreas is commonly located just below the origin of the superior mesenteric artery (SMA). Ultrasound imaging serves as a valuable tool for acquiring detailed information about the pancreas, encompassing factors such as pancreatic size, echotexture, ductal anatomy, and the surrounding structures. This imaging modality not only facilitates diagnostic evaluations but also allows for interventional procedures, all accomplished efficiently within a brief timeframe and at a minimal cost.Methods:150 healthy adults as controls and 150 diabetic patients of age group 35-65 years were evaluated by ultrasound sonography. Results:The mean pancreatic head, body and tail size is 2.01±0.38cm, 1.26±0.18cm and 2.26±0.32 cm respectively in diabetic participants while in controls it is 2.40±0.13 cm, 1.59±0.17 cm and 2.50±0.32. This showed a significant decrease in pancreatic head size in diabetic individuals.Conclusions:Diabetic individuals exhibit smaller pancreases compared to normal controls.