Background: Selective α1-blockers are commonly administered to patients with lower urinary tract syndrome and benign prostatic hyperplasia, but may increase the risk of intraoperative floppy iris syndrome (IFIS). Aim: To Assess the floppy Iris syndrome in patients of BPH taking alpha 1 blocker. Method: 51 eyes of 45 patients who are known patients of benign prostatic hyperplasia taking alpha 1 blocker were evaluated for study.Occurrence of IFIS was noted during surgery. Results: In this prospective study we obtained data from 51 eyes of 45 Patients. All patients were male and taking alpha 1 blocker for BPH. About 45 % patients were having features of Intraoperative Floppy Iris Syndrome (IFIS). Incomplete IFIS was noted in 37.71% and complete IFIS was found in 08.80% patients. Conclusion: Selective alpha 1 blocker (Tamsulosinand Alfuzocin), which is a commonly prescribed medication for BPH patients is significantly associated with floppy iris syndrome during cataract surgery.