Background:The present study was conducted for histopathologic analysis of endometrial curettage of subjects with abnormal uterine bleeding. Materials & methods:A total of 100 subjects were analyzed during the study. Details of the study protocol was explained to the subjects.An informed consent was taken from all the subjects.History was taken.Information on regularity of the menstrual cycles was taken.All women clinically diagnosed as cases of AUB were entered this study.Endometrial curettage samples were fixed in 10% formalin and histopathological slides were prepared and stained with hematoxylin and eosin stain.Slides were examined under microscope to confirm the cause of AUB. Results:Mean age of the patients was 40.7 years.HMB was seen in 80 percent of the patients while frequent menstrual bleed and intermenstrual bleeding were seen in 62 percent and 33 percent of the patients respectively.Normal/hormonal histopathologic findings were seen in 55 percent of the patients while hyperplasia was seen in 5 percent of the patients. Polyps were seen in 29 percent of the patients (Endometrial polyp –12%; Cervical polyp – 17%). Endometrial carcinoma was present in 12 percent of the patients while cervical carcinoma was seen in 6 percent of the patients. Collectively, malignancies were present in 11 percent of the patients. Conclusion:Hormonal variations are the most common cause of AUB with Heavy menstrual bleeding being the most common clinical findings.