Background: Acute diarrheal diseases is one of the common morbid conditions encountered these days. Clinical presentation includes fever and headache without diarrhea and healthy carriers have been observed. Hence; the present study was conducted for evaluating antibiotic pattern utilization in treatment of acute diarrhea. Materials &Methods:The present cross-sectional study was conducted for evaluating antibiotic pattern utilization on the medical records of 200 patients who were treated for acute diarrheal disease. A structured questionnaire was developed based on the study objective to collect the necessary data. A Performa was made and detailed data of the questionnaire pertaining to the antibiotic prescribing pattern was recorded. Complete demographic and clinical details were also recorded separately. All the results were recorded in Microsoft excel sheet and were subjected to statistical analysis using SPSS software. Results: Cotrimoxazole was the most commonly prescribed antibiotic found to be present in 35.5 percent of the cases. Ciprofloxacin was the next number found to be present in 21.5 percent of the cases. Other prescribed antibiotics included doxycycline, gentamycin, ceftriaxone, cephalexin and metronidazole found to be present in 5 percent, 2 percent, 1 percent, 2.5 percent and 14 percent of the patients respectively. Metronidazole + Ciprofloxacin and Cotrimoxazole + Amoxycillin were found to be present in 6 percent and 6.5 percent of the patients respectively. Conclusion: There is irrational use of antibiotics for the treatment of acute diarrhea that warrants interventional strategies.