Background: The present study was conducted for determining the etiology and clinical features of seizures in critically ill children admitted to a pediatric intensive care unit (PICU). Materials &Methods:Assessment of a total of 50 subjects of less than 16 years of age was done. Only those subjects were analyzed who were presented with seizures and needed admission to intensive care unit. Exclusion criteria for the present study included pediatric subjects who were admitted to PICU for non-neurological emergencies. Complete demographic and clinical details off all the subjects were obtained. Details regarding clinical presentation, Pediatric Early Warning Signs score (PEWS) at presentation and etiological diagnosis. Results:A total of 50 patients were analyzed. The mean age of the patients was 8.9 years. The majority of subjects were girls. 24 percent of the subjects had positive history of pre-existing epilepsy.82 percent of the subjects were of high risk as per PEWS score. Most common type of seizure was generalized tonic-clonic. Mean duration of seizure was 25.3 minutes. Acute etiology was seen in 34 percent of the subjects. CNS infection was the most common etiologic type. 12 percent of the subjects had unknown etiology. Conclusion:A large number of critical children had prolonged seizures, recurrent seizures and had CNS infection as the etiology. Hence; there is a need to emphasize the scope of preventive strategies in reducing disease burden.