Original Articles
Histopathological Findings and Demographic Trends in Appendiceal Mucinous Neoplasm: A Retrospective Study | |
Minu Chandran, Reeba Mary Rajan, Apuca Susan Mathew | |
Background:Appendiceal mucinous neoplasms (AMNs) represent a rare and heterogeneous group of lesions with diverse histopathological features and clinical presentations. Understanding the demographic and clinicopathological characteristics of these neoplasms is crucial for accurate diagnosis and optimal patient management.Methods:We conducted a retrospective study analyzing seven cases of Low-grade Appendiceal Mucinous Neoplasms (LAMNs) from the archives of the Department of Pathology, Dr. Somervell Memorial CSI Medical College, Kerala. Demographic data, clinical presentations, radiological findings, histopathological features, and treatment outcomes were comprehensively evaluated.Result:The study cohort comprised seven patients diagnosed with LAMNs, with a mean age of 38.71 years. There was a slight male predominance, with 57.1% of cases being male. Histopathological evaluation revealed a spectrum of epithelial morphologies, with 57% of cases exhibiting a classic villous pattern. The majority of cases were classified as pTis stage, indicating mucinous adenocarcinoma in situ.Conclusion:Our study provides valuable insights into the demographic and clinicopathological characteristics of LAMNs, highlighting the variability in gender distribution and histopathological patterns observed. The prognostic significance of LAMN staging underscores the importance of accurate diagnosis and staging for optimal patient management. |
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