Background: The present study was conducted for analyzing serum renal profile in liver cirrhosis patients. Materials & methods:A total of 100 patients with diagnosis of Cirrhosis liver of varied etiologies were enrolled. Complete demographic and clinical details of all the patients was obtained. Blood samples were obtained and serum renal profile was evaluated. All the patients were graded according to Child-Pugh scoring. According to it, Grade A represented minimal severe grade while Grade C represented maximum severity. All the results were compiled and analyzed by SPSS software. Results:Mean blood urea levels and serum creatinine levels were found to be 38.14 mg/dL and 1.23 mg/dL respectively. Raised renal profile was present in 35 percent of the patients. While analyzing the correlation of renal profile with severity of liver cirrhosis, it was seen that higher severity grade of liver cirrhosis was associated with deranged renal profile. Conclusion:Renal profile should be carefully monitored in liver cirrhosis patients.