Background:The present study was aimed to evaluate the thyroid hormone levels in healthy newborns born to mothers with hypothyroidism during pregnancy. Materials & methods:A total of 100 pregnant subjects were enrolled. All the subjects were divided into two study groups with 50 subjects in each group: Study group (Hypothyroid pregnant subjects), and Control group. On day 4 of life a plain venous blood sample was collected for evaluation of thyroid profile and results were analyzed statistically. All the results were recorded in Microsoft excel sheet and were subjected to statistical analysis using SPSS software. Chi-square test and student t test were used for evaluation of level of significance. Results:82 percent of the subjects of the study group and 90 percent of the subjects of the control group were appropriate for gestational age. While comparing the weight for gestational age among the two study groups, significant results were obtained. While comparing the thyroid profile among the two study groups, non-significant results were obtained. Conclusion:Thyroid disorders during pregnancy do affect the fetal development. Prematurity and dysmaturity may compromise neonatal thyroid function, leading to transient or permanent thyroid dysfunction, and to metabolic and cardiovascular disorders.