Background: It has been determined that hepatitis viruses A–G are the causative agents of several liver diseases. The present study was conducted to assess clinical profile and hematological parameters in acute and chronic liver diseases.Materials & Methods: 60 patients with liver diseases of both genders were included. Detailed history, physical examination, and necessary investigations such as blood urea, serum creatinine, urine analysis ix. USG abdomen, liver function tests such as HBsAg, anti-HCV, liver biopsy, reticulocyte count, prothrombin time, etc. were recorded.Results: Out of 60 patients, males were 39 and females were 21. In the present study, majority of the patients consumed >60 grams/24hrs (56.6%) of alcohol, 30.8% of people consumed 50- 60 gm /24 hrs and 12.6% consumed 50 gm /24 hrs. Symptoms were nausea/vomiting in 45, jaundice in 37, fever in 21, abdominal extension in 15, pain abdomen in 22, G I bleeding in 10 and altered behaviour in 7 patients. The difference was significant (P< 0.05). In present study enzymes AST, ALT and ALP was raised in 66.66% cases. The serum bilirubin ranged from 3.6 mg/dl to 8.8 mg/dl. Bilirubin was raised in 80.0% cases, albumin in 41.66% cases and Globulin in 50.0% cases.Conclusion: Chronic alcohol consumption is more common in adult males. Chronic alcoholics consume more amount of alcohol. Alcoholic liver disease has a varied clinical presentation and is associated with deranged biochemical parameters.These biochemical parameters may help clinicians to support the diagnosis of ALD and non-ALD.