Oral and maxillofacial surgeries involve surgical manipulation of facial skeletal elements and thus have marked impact on the cardiovascular stress response, which can result in a significant increase in the MAP and HR. After obtaining approval from the ethics committee, data was collected from patients coming to Institute of Oncology for elective mandibulectomy/maxillectomy surgeries performed under General Anaesthesia. Patients fulfilling the inclusion criteria were briefed about the procedure and written informed consenttaken. Patient demographic details noted. Difference in HR between BL, BI shows no statistical significance difference at p > 0.05 level, whereas in 15 AI, 30AI,45AI,60AI,90AI,120 AI,150AI, 180 AI,5BE shows highly statistical significance difference at p<0.01 level respectively.