Aim: Comparative clinical assessment of spinal anesthesia with Levobupivacaine alone vs a combination of Levobupivacaine and Dexmedetomidine. Materials and Methods: A total of 140 patients, classified as American Society of Anesthesiologists physical status I or II, were included in this randomized, double-blind trial. The patients were of both sexes, aged between 30 and 70 years, with a body weight ranging from 40 to 80 kg and a height more than 150 cm. The groups were segregated and treatment was administered in the following manner: Control Group (Group-A, N=70): 0.5% Isobaric levobupivacaine 15 mg (3 ml) with 0.3 ml normal saline; Study Group (Group-B, N=70): 0.5% Isobaric levobupivacaine 15 mg (3 ml) with 0.3 ml (3 μg) dexmedetomidine. Results: The average time it took for the sensory block to reach the T10 dermatome was 8.78 ± 0.66 minutes in Group A (Levo) and 5.27 ± 0.39 minutes in Group B (Levo+Dex) (P<0.05). In the Levo group, the median maximum sensory level reached was at the T6 dermatome in 18.22 ± 1.17 minutes. In the Levo+Dex group, the median maximum sensory level was at the T4 dermatome in 10.12 ± 1.15 minutes (P<0.01). The average length of sensory block, measured as the time it took for the regression to the S1 dermatome, was 212.19 ± 7.92 minutes in Group Levo and 361.11 ± 12.92 minutes in Group Levo+Dex (P < 0.01). The average duration required to reach maximal motor block was 13.48 ± 0.76 minutes for the Levo group and 9.11 ± 0.85 minutes for the Levo+Dex group (P<0.01). In addition, the average duration of motor block in Group Levo was 139.19 ± 5.39 minutes, whereas in Group Levo+Dex it was 184.93 ± 5.79 minutes. Both differences exhibited a high level of significance (P < 0.001). Conclusion: Our observation indicates that the combination of levobupivacaine and dexmedetomidine is effective in achieving surgical anesthesia and maintaining stable hemodynamics. This combination outperforms levobupivacaine alone in several aspects: it leads to a faster onset of sensory and motor block, a longer duration of sensory and motor block, a prolonged period of postoperative analgesia, and a reduced need for rescue analgesia.