Background:Coronary heart disease (CHD), sometimes referred to as ischemic heart disease or coronary artery disease (CAD), is a medical disorder that arises when the accumulation of plaque in the coronary arteries reduces or blocks the blood supply to the heart's muscles, or myocardium. The present study was conducted to assess risk factors for coronary artery disease. Materials & Methods:65 patients of coronary artery disease of both genderswere enrolled. Assessment of weight (Kg) and height (cm) and body mass index (BMI) was calculated. Measurement of plasma glucose, HLD-C, LDL-C, and ALT. Results: Out of 65 patients, males were 40 and females were 25. The age >45 years had 20 and <45 years had 45 patients. Education status was primary in 20, secondary in 22 and higher in 23 patients. Disease type was hypertension in 7, CHD in 28 and HTN & CHD in 30 patients. Smoking was positive in 42 and negative in 23. Alcohol intake was positive in 42 and negative in 23. Marital status was married in 38 and unmarried in 27. Family history was positive in 34 and negative in 31. Physical activity was positive in 19 and negative in 46. The difference was significant (P< 0.05). The risk factors were ALT with normal level in 22 and high in 43 patients. LDL- C was normalin 18 and high risk in 47. HDL- C was normal in 16, moderate in 24 and high in 25 patients. The difference was significant (P< 0.05). Conclusion: High LDL-C, an ALT level, smoking, drunkenness, inactivity, obesity, and a favorable family history were all prevalent risk factors for CHD.