The incidence of cutaneous drug eruptions is about 2.2% and is higher among inpatients and females. Fatal reactions to drug occur even though benign reactions are common. The diagnosis of cutaneous drug reaction is based on detailed history and correlation between drug intake and the onset of rash. A stepwise approach was taken to evaluate the patients. This included an exhaustive history and clinical examination. An accurate drug history was obtained. Names of all the drugs and the duration of intake were noted. Attention was also paid to the sequence of events, to rule out other diseases mimicking drug rash. The underlying disease for which drug was taken was also noted. History of any previous drug allergies in self and family members, were also noted. The most common cutaneous adverse drug reaction seen in our patients were maculopapular rash in 23% (23/100), followed by fixed drug eruptions in 17% (17/100), urticaria in 10% (10/100), Stevens Johnson syndrome in 9% (9/100), DHS in 8% (08/100), and acneiform in 6% (06/100). A similar pattern was seen in the adult age group.