Background: The present study was conducted for assessing the effects of smoking on common carotid intima-media thickness and resistivity index among current smokers.Materials & methods:A total of 100 current smokers and 100 non-smokers were enrolled in the current research. Current smokers were defined as subjects who had smoked within the previous 30 days and/or had smoked 100 cigarettes in his or her lifetime.Any CIMT thickness over 0.8 mm was regarded as abnormal. A localized protrusion of the vessel wall that expanded into the lumen by ≥1.5 mm was identified as the plaque. Bilateral CIMT and RI values were acquired. The RI was calculated according to Pourcelot equation. All the results were recorded in Microsoft excel sheet followed by statistical analysis using SPSS software.Results:Mean CIMT value among current smokers and non-smokers was 0.655 and 0.545 respectively. Mean CIMT values of smokers was found to be significantly raised in comparison to that of non-smokers. Mean RI value among smokers and non-smokers was 0.725 and 0.73 respectively. On comparing, the results were found to be statistically significant.Conclusion:Smoking leads to morphological alteration in CCA as depicted by altered CIMT.