Background:Most parents have a poor understanding of vaccine-preventablediseases and believe in false propagations about the contents, side effects, and effectiveness of vaccines. This study was conducted to assess the profile of infant with their caregiver and awareness regarding immunization among the caregivers who were attending Immunization Clinic.Material and Methods :The present cross-sectional study done on the 450 Caregivers of infants up to 1 year of age who gave consent to participate in the study. The descriptive representation of data was done in the form of numbers and percentages, calculated in MS Excel. Results:The majority of infants i.e., 183(40.6%) were 2-4 months of age, came at 5th visit for vaccination (32%), 61.8% were males and belonged to the general category (53.3%). Hindus caregivers were observed in preponderance (90.4%). Mostly infants were from urban areas i.e., 436(96.9%).This table shows that more than 3/5th of infants were born with ≥2.5 kg birth weight i.e., 292(64.9%).About half (55.6%) of the infants were at the first birth order. The majority of caregivers i.e., 449(99.8%) had already heard about immunization and 77.8% had the knowledge that immunization prevents morbidity from a certain specific disease. Maximum proportion of caregivers got information about immunization through Anganwadi Workers i.e., 287(63.7%). Conclusion:Immunization can prevent many morbidities, mortalities and disabilities. In this study, majority of infants were males, were in age group of 02-04 months, belonged to general category and Hindu families living in the urban area. Most of the parents were graduates,living in joint families, and belonging to upper middle class. In this study, almost all caregivers were already heard about immunization and knew that immunization was necessary and 77.8% knew that immunization prevent morbidity due to certain specific disease.