Aim: The aim of the present study was to evaluate the efficacy, safety and advantages of conducting Laparoscopic Cholecystectomy under Spinal Anaesthesia (SA) in comparison to General Anaesthesia (GA). Methods: The study was conducted in the Department of Anaesthesiology. Informed consent was obtained from all the patients who had agreed to participate in the study. A detailed explanation of the procedure and risks involved was given. A total number of 50 patients were included in the study. Results: Both groups had comparable demographic characteristics. Within the SA group, there were 33 female patients and 17 male patients. The average age was 46 ±12.68 years in the SA group and 48.82 ±10.45 years in the GA group. The surgical procedure lasted for an average of 82.98±21.99 minutes in the GA group and 98.2±36.04 minutes in the SA group. However, this difference in time between the two groups did not reach statistical significance. Out of the 6 patients, 2 had persistent shoulder discomfort even after receiving Inj. fentanyl and had to be given general anaesthesia. These 2 patients were therefore eliminated from the further study. All patients in the SA group did not have immediate postoperative discomfort at the location of the operation. In the first 24h tramadol required as rescue in the GA group was 84±26 mg which was significantly higher than the SA group requiring only 31±32.18 mg.Although the GA group had a higher incidence of postoperative nausea and vomiting, this difference was not statistically significant. There were no instances of postoperative infections or headache among the patients. Conclusion: Our findings indicate that laparoscopic cholecystectomy may be safely conducted with the use of spinal anaesthesia with hyperbaric bupivacaine, and fentanyl as adjuvant. Spinal anaesthesia offers consistent intraoperative hemodynamic and respiratory parameters, requires fewer postoperative analgesics due to its prolonged analgesic effects, and is associated with less problems and higher patient satisfaction.