Background: Brain abscess is an intraparenchymal collection of pus. It can occur due to spread of infection from a contiguous focus, hematogenous seeding from a distant source, as a sequelae of head trauma or neurosurgical procedure. The present study was conducted to assess incidence of brain abscess in patients coming to the department of Neurosurgery. Materials & Methods: The present study was conducted to assess incidence of brain abscess in patients coming to the department of Neurosurgery over a period of one year. All patients suspected of having brain abscess on basis of clinical history, CT scan and MRI, of all groups and genders were included in the study. The collected data were analysed using SPSS version 16.0 software. Results: In the present study 410 patients were reported to the department in which 50 patients were included based on history, examination and investigations were done. The total incidence of brain abscess was 12.19%. The brain abscess was prevalent in males (56%) than females (44%). The brain abscess was more common in age group 31-40 years followed by age group 18-30 years. Conclusion: The study concluded that the total incidence of brain abscess was 12.19%. The brain abscess was prevalent in males than females. The brain abscess was more common in age group 31-40 years followed by age group 18-30 years.