Original Articles
Lipid profile analysis of patients with high blood pressure and correlation between hypertension and lipid profile in normal and pre-hypertensive patients | |
Pankaj Bohra, Amitesh Nagrwal | |
Introduction: Therefore increased level of blood lipids signify the increased cardiovascular risk in subjects suffering from prehypertension. So early detection of this derangement and early intervention may arrest the progression of prehypertension to hypertension and prevent the complications of individuals suffering from hypertension. Our aim was to find the evaluation of lipid profile among pre-hypertensive and normotensive and its correlation between blood pressure and lipid profile in pre-hypertensive patients. Materials and Methods: Blood pressure was measured with the sphygmomanometer from the right arm of seated participant after five minutes rest and was recorded using 1st and 5thkorotkoff sounds. The appearance of 1stkorotkoff sound was taken as systolic blood pressure (SBP) and 5thkorotk off sound was taken as diastolic blood pressure (DBP). Three blood pressure measurements were taken and the mean of the last two measurements were used for analysis. 5 ml of venous blood was collected after overnight fasting of 12 hrs in all the subjects for estimation of serum total cholesterol, HDL cholesterol, LDL cholesterol, VLDL cholesterol, and serum triglyceride by standard enzymatic method. Result: Comparison of basic characteristics like age, height, weight and BMI between two groups did not show significant different between the two group (p>0.05). The two groups were similar in terms of basic characteristics. Conclusion: The higher level of serum TC, TG and LDL- cholesterol in the study population may be due to genetic factors and increased consumption of dietary animal fat, lack of physical exercise, metabolic disorders like diabetes mellitus and hypothyroidism, severe stress, increased age, sex as well as alcohol and tobacco consumption may also be the contributory factors for this phenomenon. |
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