Background: A neonate is defined as a newborn under the age of 28 days by the World Health Organization. Due to the infant's weakened immune system and several morbidities, the neonatal period is critical. When a newborn exhibits any morbidities, the neonatal intensive care unit is notified (NICU). Kerala records the lowest neonatal mortality rate in the entire country. However, various maternal and neonatal factors and even incidents during labor can increase the probability of newborn morbidity and hence this study is an effort to estimate the prevalence of NICU admissions among newborns delivered and to enumerate the morbidity pattern and outcomes among the neonates admitted in a tertiary care center in South Kerala. Materials and Methods:A retrospective cross-sectional study of 511 live births and NICU admission records of the neonates were collected from MRD over 8 months. After taking permission of Institutional authorities, a Semi-structured questionnaire was used to collect the data regarding birth, neonatal admission, morbidity pattern and outcomes from the records. Results: Prevalence of NICU admissions among newborns was found to be 42.86%. Jaundice (54.4%) was found to be the major cause of NICU admission. Most of the neonates got cured and discharged (96.8%) with the majority of them staying for a period 4 to 6 days (64.4%). Maternal age group and delivery of preterm neonates <35 weeks, mode of delivery and low birth weight, mode of delivery and respiratory distress, birth weight and preterm neonates were found to have statistically significant association. Conclusion: Prevalence of NICU admission in the study area was high (42.8%) and the major morbidity patterns contributing to NICU admission were found to be jaundice followed by respiratory distress.