Background: The status of diabetes has changed from being considered as a mild disorder of the elderly to one of the major causes of morbidity and mortality affecting the youth and middle-aged people. The present study was conducted to assess CRP level in diabetes mellitus patients. Materials & Methods: 50 type 2 diabetic patients and 50 were apparently healthy non-diabetic persons of both genderswere subjected to an assessment of fasting blood glucose, random blood glucose and CRP level. Results: Out of 50 patients, males were 30 and females were 20. The mean FBG in group I and group II was 176.2 mg/dl and 90.4 mg/dl, RBG was 242.6 mg/dl and 146.8 mg/dl and CRP was 15.7 mg/l and 6.0 mg/l respectively. The difference was significant (P< 0.05). Conclusion: There was increased level of high-sensitivity C-reactive protein in type II diabetes patients.