Introduction: Alcohol abuse is a global health concern, contributing significantly to morbidity, mortality, and societal costs. In India, alcohol dependence affects approximately 2.7% of the population, leading to substantial health, social, and economic consequences. This study aims to investigate the sociodemographic and clinical characteristics of alcohol dependence patients in a tertiary care center, offering insights for more effective preventive and treatment strategies. Aims & Objectives: To Study the sociodemographic and clinical profiles of individuals admitted with alcohol dependence in a de-addiction ward at a tertiary care center. Methodology: This observational study enrolled 100 male patients using purposive sampling. Inclusion criteria involved patients meeting WHO ICD-10 criteria for dependence syndrome, aged >18 years, admitted as inpatients, providing informed consent, and having reliable informants. Data was collected using a semi-structured proforma, WHO ICD-10 criteria, Severity of Alcohol Dependence Questionnaire (SADQ), and Clinical Institute Withdrawal Assessment of Alcohol Scale (CIWA-Ar). Results: The majority of participants were aged 26-35 years (48%), Hindus (94%), urban residents (80%), and educated up to the middle class (49%). Most were married (83%) and had a joint family (53%). In terms of clinical profiles, the majority initiated alcohol use between 15-25 years (59%), had a family history of substance abuse (64%), and experienced complicated withdrawals (29%). About 25% of patients had legal issues related to alcoholism. The mean CIWA score was 9.5 (SD 4.8), and the mean SADQ score was 15.84 (SD 9.2). Discussion: The study revealed a male preponderance in alcoholism, possibly influenced by societal stigma regarding female healthcare access. Demographics reflected regional cultural and socio-demographic patterns. Early onset of alcohol use and a family history of substance abuse were prominent. Complicated withdrawals and legal issues underscored the severity of alcoholism. The study's limitations include its single-center nature and potential response bias. Conclusion: This study sheds light on the sociodemographic and clinical factors associated with alcohol dependence in a specific region of India. Understanding these factors is crucial for tailoring effective prevention and treatment strategies. Clinicians should focus on early intervention and individualized relapse prevention in this population. Further research with larger sample sizes in diverse settings is recommended.