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Volume 12 Issue 2 ( April- June) 2023

Original Articles

Malignant solid tumors and lymphomas in children: Analysis of pattern in the India
Dr. Mahendra Kumar Balot, Dr. Gireesh Mishra, Dr. Balendra Singh Sodhi, Dr. Abhishek Gupta

Background: Globally, childhood cancer incidence and mortality rates vary. In order to help with the design of treatment facilities and to learn more about the etiology, it is crucial to study incidence patterns and survival rates for childhood cancers. There are not many studies that look at survival rates for childhood solid tumors in India. Objective: Evaluation of the patterns, frequency, and prognosis of solid tumors and lymphomas in children admitted to and followed up at the Pediatric Oncology Department. Methods: A retrospective study involving 104 kids with solid tumors and lymphomas was carried out. Under the supervision of ophthalmologists, neurosurgeons, and orthopaedics, the medical records were examined, and pertinent data was gathered, including demographic, clinical, histopathological, laboratory, and imaging data. Results: The mean age of patients was 3.6±3.66 years at diagnosis. The patient population was split between 61 men and 43 women. The most frequent tumor type was non-Hodgkin lymphoma (NHL), followed by neuroblastoma (14.4%) and Hodgkin lymphoma (10.6%), in that order. The <5-years-of-age group exhibited the greatest number of patients when patients were stratified in terms of age (<5, ≥5 - <10, and ≥10 years). The most frequent initial clinical manifestations among the patients were fever, pallor, and pain. Stage II was the most prevalent stage (36.5%), then stage I, stage III, and stage IV. The study group's overall 5-year survival rate was 71.7%. Conclusion: The most prevalent tumors were NHL, HL, and neuroblastoma. To further explore the findings from this study, a larger multicenter study is needed.

 
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