Background: This study was conducted for the Prediction of preeclampsia using uterine artery Doppler pulsatility index between 11-14 weeks.Material and methods: All subjects were informed about the study and informed consent was taken before they were enrolled in the study. Women were subjected to detailed history and gestational age was calculated from reliable last menstrual history and early ultrasound. Family history, past medical history, smoking habits, medical histories of first degree family members was taken. Systemic examination with special reference to edema, blood pressure and gestational week was carried out. Results: Atotalof 62% ofwomenwere18-25yearsofage,34%were26-30yearsofage and only 4% were more than 30 years of age. Mean age was 24.6yearswithyoungest women was 19 yearsofage and oldest 32 yearsofage.Conclusion: Thus we can conclude that Pre-eclampsia is believed to develop from inadequate trophoblast invasion of the maternal spiral arteries and Doppler ultrasound is a reliable, noninvasive method of examining uteroplacental perfusion. Abnormal UA Doppler ultrasonography (elevated PI) in 11–14 weeks' gestation can predict pre-eclampsia. It is recommended to follow-up cases presenting with a high PI at the 11–14 weeks' scan for development of Pre-eclampsia. Doppler imaging permits non-invasive evaluation of the uteroplacental circulation, thus enabling further earlier prevention and therapeutic interventions to improve maternal and neonatal health.