Background: Diabetes currently affects more than 66.8 million people in India, which has become a major health care problem, representing the largest number of any country in the world. Reduced concomitant intake of Zinc has been proven to be associated with increased HbA1c percentages in individuals with Type 2 diabetes. Aims and Objectives: The current study was designed to assess serum Zinc levels in Type 2 Diabetes patients and to find out the correlation between serum Zinc and HbA1c levels in Type 2 diabetes patients. Materials and Methods: The present case-control study was conducted on Type 2 Diabetes mellitus patients attending the OPD of General Medicine in collaboration with the Department of Pharmacology at Bhagwan Mahavir Institute of Medical Sciences, Pawapuri, Nalanda, Bihar, India. The sample of the study was 80 old and new patients of Type 2 Diabetes Mellitus who were included in the study, consisting of Group I (45 patients): Type 2 Diabetic patients with HbA1c more than 7 percent and Group II (35 patients): Type 2 Diabetic patients with HbA1c less than 7 percent after taking informed consent. Results: The mean age of study group was 52.64±12.36 years and control group was 56.72±10.28 years respectively. A case-control study was conducted with 80 type 2 diabetic patients who were divided into two groups consisting of 45 type 2 Diabetic patients with HbA1c >7 percent in Group I and 35 type 2 diabetic patients with HbA1c <7 percent in Group II. Serum Zinc has a strong negative correlation (r = -0.409) with HbA1c in the Type 2 diabetic patients with HbA1c >7 (p = 0.001). Conclusion: By comparing the levels of HbA1c and serum zinc in Type 2 DM patients, it is possible to monitor glycaemic control and lower the risk of developing complications. Key words: HbA1c; Serum Zinc; Microalbuminuria; Diabetes; Complications