Introduction: All operative wounds are contaminated by micro-organisms but only a minority actually presents clinical infections.Superoxidized Solutions have shown to be both safe and efficient as a wound care product that moistens, lubricates, debrides and reduces the microbial load of various types of lesions. The present study was done to compare the effect of superoxide solution (oxum) v/s eusol in surgical wounds dressing. Material and methods: All patients admitted to the surgery wards at Guru Nanak Dev Hospital, attached to Govt. Medical College, Amritsar, who underwent any sort of surgical intervention were included. Twenty five patients were included in GROUP A where dressing and management was done using superoxide solution(OXUM) and twenty five patients in GROUP B where dressing and management was done using EUSOL. In both the groups attempt was made to include similar type of wounds. Antibiotics were used in both the groups after taking a swab for culture and sensitivity prior to dressing. Results:Swab culture was found to be more positive in GROUP B compared to GROUP A. Most common organism found positive were pseudomonas, staphylococcus and E.coli. There were many host factors contributing to delayed wound healing like old age, diabetes mellitus, obesity etc. Superoxide solution and EUSOL both are safe and effective antiseptic solutions and capable of reducing microbial numbers or bacteria present on the wound. Our study observed that there was remarkable reduction in signs of inflammation like oedema and erythema and remarkable increase in signs of healing of the ulcer i.e.granulation and fibrin formation. Healing time was faster in GROUP A compared to GROUP B so as less hospital stay in various categories of wound observed in group A compared to group B. Less morbidity ,more improvement and,higher cure rate was seen in group A compared to group B. Treatment with superoxide solution reduces the microbial flora and less painful during cleaning and debridement of wound. Example diabetic foot ulcers,venous stasis ulcer,burns,cellulitis etc where superoxide solution can be used safely. Wounds treated with OXUM heals with better cosmetic results. Easily applied and less expensive due to reduced hospital stay. Conclusion: it was concluded that OXUM shows more favourable results than EUSOL. Key words: Eusol, Oxum, Wound infection