Background: Although oral mucosal lesions (OMLs) are not morbid, occurrence of this often affects routine work, social appearance and mastication and swallowing. Region-wise prevalence studies helps to estimate the various strategies to prevent this condition. Objective: To determine the prevalence and distribution of OMLs of patients visited for oral and dental problems. Methods: All patients visiting to outpatient department were evaluated for oral problems and those with OMLs are selected for further investigations. Demographic characteristics were evaluated for these patients and were grouped based on age. Oral examination was performed using the Color Atlas of Common Oral Diseases and based on the history and clinical appearance; the OMLs were grouped in different categories. Results: Among 1600 patients, 625 (39.06 %) were identified to have OMLs. We found male predominance 69.12% vs 30.88%in the OMLs. Patients with age >41 years (40.96%) are more susceptible for the development of these lesions and it is gradually decreases as age groups (36-41 years, 19.68%; 30–35 years, 13.76%; 24–29 years, 15.04% and 18–23 years, 10.56%). Most common OMLs were tobacco related lesions (n=222, 36.09%) followed by tongue lesions (n=116, 18.86%). Conclusion: The prevalence of oral mucosal lesions was more in the males and age more than 41 years. Tobacco consumption was found be another factor for the development of OMLs. The high prevalence of OMLs necessitates adequate awareness and management of these lesions in the general population. General practitioners and dental clinicians need to be more aware to conduct such studies to help developing strategies for future prevention.