Background: The present study was conducted for assessing the effect of diabetes on the osseointegration of dental implants. Materials & methods: A total of 100 subjects with presence of diabetes were enrolled. Only those subjects were enrolled which had missing mandibular first molars and were scheduled to undergo prosthetic rehabilitation for the same with dental implants. Radiographic analysis was done and all the patients underwent dental implant procedures. All the patients were recalled and radiographic examination along with clinical evaluation was done for assessment of osseointegration. All ‘failed’ implants needed to be removed. All failed dental implants were considered to be failed because of lack of osseointegration. All the results were recorded in Microsoft excel sheet and was subjected to statistical analysis using SPSS software. Results: A total of 100 patients were evaluated. Mean age of the patients was 45.6 years. Out of 100 patients, 59 patients were males while the remaining were females. Out of 100 patients, radiographic success as defined by successful osseointegration was seen in 95 patients. Among the 5 patients, in which there was failure of osseointegration, mean HbA1c levels were more than 8%. Conclusion: Under controlled diabetic conditions, dental implants are accompanied by successful osseointegration.