Introduction: The choice of career is a critical discussion that has an obvious impact on future life pattern. Wrong choice causes a decrease in a country’s scientific level, waste of human and economic resources, incuriosity, and lack of student motivation toward social issues and mental disorders in the student’s personal and social life. Hence present study was conducted to evaluate the preference of career choice and motivational factors affecting the preferences of choosing different medical careers of undergraduate medical students preparing for Common entrance examinations after intermediate level examinations. Materials and Methods: The present study is a questionnaire-based cross-sectional survey. A closed ended questionnaire was used to collect the data. The questionnaire includes socio demographic details, in addition students will be asked to select their first career choice and related questions. The data were compiled and tabulated in Microsoft Excel spreadsheet and were subjected to descriptive analysis using the Statistical Package for the Social Sciences software (SPSS) 21.0 (SPSS Inc., Chicago, IL, USA).Assessments of reasons for choosing preferred medical field according to gender of medical aspirants were done using Chi-square analysis. Any P ≤ 0.05 was considered statistically significant. Results: A total of 368 participants completed the entire questionnaire and were include in the study. In the study, 41.84% opted Bachelor of Science in Nursing (B.Sc. Nursing) for future medical careers other than MBBS while 23.09% opted Bachelor of Dental Surgery (BDS). The reasons found for choosing preferred medical field according to gender of participants were found to be significant in relation to influence of family/peer pressure/friends for above chosen specialty, high income potential, stable and secure future, good Reputation, better lifestyle/prestige and good job opportunities in abroad (p≤0.001). Conclusion: According to the present study results, other than MBBS, majority of students chose Bachelor of science in Nursing (B.Sc. Nursing) as a carrier option as compared to Bachelor of Dental Surgery (BDS). Even though the reason for choosing the students preferred carrier includes high income potential, stable and secure future, good reputation, better lifestyle/prestige, good job opportunities in abroad; the influence of family/peer pressure/friends for choosing their specialty is an important factor because this may have a negative impact on students future.