Background: It goes without saying that patients undergoing orthodontic treatment must have sound and robust periodontal health. Does this imply that we will refuse orthodontic treatment to the growing number of individuals who experience aesthetic and functional issues more frequently as a result of periodontal disease and pathological tooth migration? In order to restore periodontal health, an integrated strategy is required, in which orthodontic treatment is administered after periodontal therapy. To position the teeth in a structurally balanced and functionally effective posture, orthodontic treatment should be carried out under strict plaque control procedures. Aim: To familiarize the practicing clinicians both in the field of orthodontics and periodontics with current thoughts and successful clinical techniques used in the field of periodontology to regenerate lost periodontal structures. Furthermore, it aims to integrate such techniques into the orthodontic treatment of patients with severe bone loss. Material and methods: This study had 100 individuals in total. Between the test and control groups, a 1.0 mm difference in clinical attachment level (CAL) was deemed clinically significant. The control group included patients handled by obtaining and maintaining stable periodontal health, while the test group included individuals getting orthodontic treatment after treatment for periodontitis. 50 patients in each group were required to detect a clinically significant difference in CAL of 1.0 mm, standard deviation (SD) of 1.0 mm, with a power of 80%, and a -level error of 0.05.At T0, parameters were recorded for each of the 100 patients who underwent a thorough periodontal evaluation. Block randomization was completed by an investigator (DK) who was not involved in administering orthodontic or periodontal therapy, analysing data, or achieving periodontal stabilisation. Using random allocation software, various balanced combinations of three tests and three controls were created in blocks of six. For the assignment of each block to each participant, another random selection of blocks was made. The research design did not blind clinicians or patients. However, because all patients and their data were numbered consecutively, the person analysing the data was blinded. Results: In this study, all the 100 patients completed the trial, and healing was uneventful in all patients. There were no statistically significant differences at baseline in demographic, clinical, or radiological parameters between the two groups.All clinical periodontal markers in both groups improved statistically significantly (P >.05) over time, with no discernible differences between the groups. Conclusion: Orthodontic treatment after periodontal stabilization does not have any detrimental effect on periodontal health in adult periodontally compromised orthodontic patients and may add to the benefits achieved by periodontal treatment alone.