Background: Tobacco use is a global epidemic among young people. The present study was conducted to assess the outcome of tobacco cessation among subjects with tobacco habit. Materials & Methods: The present 5 years retrospectives study was conducted on 520 subjects of both genders (males- 340, females- 180) in the age range of 20- 50 years. All cases were of leukoplakia, OSMF, oral cancer etc. who were diagnosed 5 years back and advised to discontinue the habit or were treated accordingly. Careful clinical examination was done to detect presence of any lesions. Results: Age group 20-30 years had 150 males and 80 females, 30-40 years had 110 males and 70 females and 40-50 years had 80 males and 30 females. The difference was significant (P< 0.05). Leukoplakia was seen in 165, Smoker’s palate in 78, Smoker’s melanosis in 210, OSMF in 45 and oral cancer in 22 before 5 years and which decreased to 52, 12, 43, 8 and 4 after 5 years respectively. 60% cases adopted nicotine replacement therapy, 20% intralesional injection, 20% surgery and 2% radiotherapy. The difference was significant (P< 0.05). Conclusion: Tobacco usage is increasing among young adults. However, with population awareness programmes the harmful effects of tobacco may be minimized.