Post-operative wound infection rate in implants and prosthesis is reported to be betweentwo and thirteen percent. This makes it not only a problem to the surgeon but to all who have astake in the care of Orthopaedic and trauma patients. The microbiology of post-operative woundinfection in implants has changed very little over time except for the emergence of resistantorganisms. Approval was obtained from the institutional ethical committee before the commencement of the study.Informed consent was obtained from the study population.All patients satisfying the inclusion criteria were documented. Patients were interviewed by structured questionnaire.In this study, the rate of proportion of risk factors was smoking 53 (68.83%) followed by alcoholism 43 (55.84%), open fracture 14(18.18%), UTI 13 (16.88%), DM 8(10.38%), anemia 6 (7.79%), malnutrition 5 (6.49%) HTN 4 (5.19%),and old age 2 (2.59%). Cefoxitin and Oxacillin disc sensitivity done on Muller-Hinton agar revealed that 14 (46.87%) were Methicillin resistant Staphylococcus aureus and 18 (56.25%) were Methicillin sensitive Staphylococcus aureus.