Introduction: Obsessive-compulsive disorder (OCD) is a chronic mental disorder characterized by obsessions and compulsions. Concerns about one's appearance are recognized and accepted in most cultures as an aspect of normal human behavior. However, if these concerns are excessive and are either significantly distressing or having an impact on the individual's quality of life, the person may be suffering from Body Dysmorphic Disorder (BDD).BDD is an obsessive-compulsive related disorder.The present study was carried to evaluate psychiatric comorbidities and the risk of suicide in obsessive-compulsive and body dysmorphic disorder.Materials and Methods: The inclusion criteria were framed as per internationally standardized PICOS framework, as recommended by PRISMA guidelines. The study population included psychiatric patients who had psychiatric Comorbidities and the Risk of Suicide in Obsessive-Compulsive and Body Dysmorphic Disorder.Results: After evaluation of 89 papers, only 6studies were ascertainedfor analysis after these papers fulfilled both inclusion and exclusion criteria. The present study reveals that body dysmorphic disorder (BDD) and OCD are associated with suicidality ideation. The combination of exposure and response prevention therapy and pharmacotherapy was reported to be effective in helping the patient manage the anxiety and distress stemming from the patient’s OCD with suicidal obsession. Conclusion: Overall, suicidality appears a relevant phenomenon in OCD. Certainly, BDD remains underdiagnosed due to a variety of factors which means patients are unlikely to receive the treatment they require and continue to suffer. Personality traits such as alexithymia and perfectionism may contribute to high suicidality in patients with OCD, and patients suffering with unacceptable thoughts need to be assessed more carefully for warning signs of suicide. Thus, patients with OCD are at a substantial risk of suicide. Importantly, this risk remains substantial after adjusting for psychiatric comorbidities. Suicide risk should be carefully monitored in patients with OCD. Particular attention should be given to comorbidity with depressive symptoms.