Propofol is commonly used for the intravenous induction of anesthesia during laryngeal mask airway (LMA) insertion due to its suppressant effect on airway reflexes. However, bolus propofol administration has been associated with adverse effects such as hypotension, apnea, and pain on injection, thus it is crucial to explore suitable alternatives. Sevoflurane, a volatile anesthetic agent, offers advantages such as smooth and rapid inhalational induction of anesthesia and quick recovery, making it well-suited, for day care anesthesia. With its low blood gas solubility and minimal respiratory irritant properties, sevoflurane is particularly suitable for inhaled induction of anesthesia and LMA insertion. The LMA technique, serving as an alternative to end tracheal intubation, is employed for securing the airway during short surgical procedures requiring general anesthesia. This study aims to compare the effects of sevoflurane and propofol on patients undergoing laryngeal mask airway insertion. (1-3)A total of 110 patients were randomly assigned to two treatment groups. Group S consisted of 55 patients who received inhalational induction with 8% sevoflurane, while Group P included 55 patients who received intravenous injection of propofol 2.5mg/kg administered intravenously over 30 seconds. In this randomized prospective study, we found that the two groups' rates of induction were remarkably similar. This study concluded that Sevoflurane required significantly more time to insert the LMA in comparison of Propofol. Both groups maintained hemodynamic stability. Consequently, Sevoflurane is a good substitute for Propofol when inserting an LMA.