Original Articles
Maternal and Fetal outcome in usage of magnesium sulphate for fetal neuroprotection in pregnancy less than 34 weeks of gestation | |
Dr. Mamatha S, Dr. Ananda M, Dr. Salma Shaziya, Dr. Manjunatha S, Dr. Somashekar HK | |
Magnesium is an essential component in the central nervous system and is irreplaceable in several metabolic functions in the cell, therefore occupying a key place in cell death and developmental processes. Although the effects of magnesium sulfate are not well understood, its neuroprotective properties can be explained by its anti-inflammatory and anti-excitotoxic effects. This is an observational study done in the Department of Obstetrics and Gynecology, Kodagu Intitute of Medical Sciences, Madikeri from November 2020- November 2021 involving 52 pregnant women. Mode of delivery, 14(27%) had term cesarean delivery,18(35%) had preterm vaginal delivery, 13(25%) had full term vaginal delivery and 7(13%) had preterm cesarean delivery. 96.2% had no reactions, minor reactions noted were tachycardia, blurring of vision, absent knee jerk only among 2 persons. Among 23 babies had normal birth weight,27 were born with low birth weight and 5 babies were born with very low birth weight.In our study 3 perinatal deaths occurred. 2 cases developed delay in development. 1 at 3 months and another 1 case had severe gross motor dysfunction at 6 months postnatal follow up. |
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