Original Articles
Evidence from a tertiary hospital in Jharkhand, "Unravelling the Interplay of Diet and Comorbidities in Vitamin B12 Deficiency: Implications for Haematological Health in a Diabetic Cohort | |
Dr. Chandra Bhushan, Dr. Shyam Kishor Pathak, Dr. Rajeev Bhardwaj | |
Introduction - Vitamin B12 deficiency is a common comorbidity among people with diabetes, and the way it interacts with diet and other health conditions can impact blood health. This study set out to explore these connections in a group of individuals with type 2 diabetes. Methods We included 420 diabetic patients in Jharkhand, India, who were found to have low levels of vitamin B12. We gathered information regarding their diets, any existing anemia, harmful habits, medical histories, B12 levels, and blood-related metrics. We then used appropriate statistical tests to analyze the data. JAMOVI latest version was used to analyse the data. p<.05 was considered statistically significant . Results Our findings indicated that those with pre-existing anemia and other deficiencies were more likely to experience severe vitamin B12 deficiency. We also discovered that severe deficiency was linked to increased mean corpuscular volume (MCV) and mean corpuscular hemoglobin (MCH). Meanwhile, having anemia was associated with lower levels of hemoglobin, red blood cell count, lymphocytes, monocytes, and MCV, but higher levels of neutrophils and MCHC. Interestingly, we didn’t find significant links between a person’s dietary habits or malabsorption symptoms and how severe their B12 deficiency was. Conclusion - The study indicates that while managing B12 deficiency in diabetic patients, knowledge of current anaemia and other deficiencies is absolutely vital since these elements might affect the degree and consequence of the deficiencies on distinct hematological profiles. This emphasises the need of taking into account dietary habits and medical conditions in effective management of these patients. |
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