Background: Ischemic stroke is one of the common neurological diseases associated with high mortality and more than half of the stroke patients remain disabled. The present study was conducted to assess cases of acute ischemic stroke. Materials & Methods: 56 cases of acute ischemic stroke admitted to neurology department of both genders. All gave their written consent to participate in the study. Data such as name, age, gender etc. was recorded. Parameters such as history, clinical examination, risk factors and CT/MRI scan of brain was done. Complete hemogram, urine routine, renal function test, ECG, chest X-ray, RBS, HbA1C and 2D Echo, CT/MRI scan done at the time of Admission. NIHSS score was noted on the day of admission and then after 30 days of stroke. Results: Out of 56 patients, males were 36 and female were 20. Clinical features were sensory deficit seen in 24, motor deficit in 30, altered sensorium in 13, cranial nerve involvement in 10, seizures in 25 and headache in 36, risk factors were HTN in 42, DM in 33, smoking in 21, alcoholism in 19 and IHD in 7, NHSS after 1 month was point 1-4 in 11, 5-15 in 27, 16- 20 in 10 and 21-42 in 8. The difference was significant (P< 0.05). Conclusion: Clinical features were sensory deficit, motor deficit, altered sensorium, cranial nerve involvement, seizures and headache. Common risk factors were HTN, DM and smoking.