Background: Pilonidal sinus disease is a common surgical disorder. The present study was conducted to assess pilonidal sinus cases. Materials & Methods: 74 cases of pilonidal sinus of both genders were included in the study. The number of sinus openings was recorded. The phenol application was made concurrently with the abscess drainage for the treatment of the acute disease. The phenol was left in situ for approximately 2 min and then expressed by pressure. Results: Age group 20-40 years had 6 males and 8 females, age group 41-60 years had 18 males and 12 females and group >60 years had 20 males and 10 females. The difference was significant (P< 0.05). 25 cases were acute and 49 were chronic. The position of orifice was midline in 32 cases and lateral in 42 cases. 21 patients had 1 application, 16 had 2, 10 had 3, 8 had 4, 10 had 5 and 9 had 6 phenol applications. The difference was significant (P< 0.05). Conclusion: Crystallized phenol can be effectively used for treatment of pilonidal disease. Maximum cases were chronic in nature.