Introduction: Penetrating Keratoplasty has been one of the most effective and successful organ transplants for over a decade. Glaucoma following penetrating Keratoplasty (PK) is one of the most common cause for irreversible visual loss and the second leading cause for graft failure after rejection. Aims and Objectives: To study the number of patients developing Glaucoma following penetrating Keratoplasty & to manage those developing the disease. Material and Methods: This is a prospective study which was conducted on 67 eyes of 66 patients with various corneal lesions attending Ophthalmic OPD of Upgraded department of MYH Indore during period from 1st Nov 2021 to 30th Oct 2022. Results: Of the 67 eyes in the present study M:F ratio was 53:14. Post op IOP was above 21mmHg in 17 cases (25.37%) while it was within normal limits i.e. < 21mmHg in 50 cases (74.62%). With increase in graft size incidence of rise in IOP increases i.e. 88.2% in cases of 8mm graft size, 11.8% in cases in 7.5mm graft size and 5.9% in cases of 7 mm graft size.Visual acuity of the cases of post PK rise in IOP preoperatively was mainly Hand movements in 12 cases (70.6%) and Perception of Light in 5 cases(29.4%). Conclusion: Raised IOP following keratoplasty is a common entity and needs to be followed up closely.