Introduction:Acute pancreatitis is the sudden inflammation of the pancreas and, to a varied degree, involves local tissues or distant organs. The severity of acute pancreatitis can be predicted based upon clinical, laboratory, and radiologic risk factors, various severity grading systems, and serum markers. Some of these can be performed on admission to assist in triage of patients The objective of the study was to determine the relation between various indices of Acute pancreatitis.Methods:A Cross Sectional analysis of Acute Pancreatitis of total 100 patients was done. Subjects included both the genders, all age groups including pediatric and geriatric age group and all classes of socio economic strata.Results: There was a significant male preponderance. Most common cause was alcohol abuse in males and gall stone disease in females. There was a good correlation between Balthazar CT severity index and Ranson‟s score. Magnitude of enzyme elevation had no relation to the severity of the disease. Irrespective of the cause enzyme elevations were similar quantitatively, but the average lipase value was higher than the average amylase value in all the etiologies. Sensitivity of the ultrasound was good while the specificity was still low. Most common complication was pseudo cyst of the pancreas. In the present study we had the objective of analysing the various severity indices. Conclusion:The initial management for an acute pancreatitis attack should be conservative; with surgery reserved for cases having uncertainty of diagnosis, trauma, very severe attacks not responding to medical therapy and complications of the disease. The severity of acute pancreatitis is variable. The ability to predict the severity can help identify patients at increased risk for morbidity and mortality, thereby assisting in appropriate triage and selection of patients for specific interventions.