Background: Urolithiasis incidence is rising globally despite significant advancements in the discovery of alternative therapies for the management of urinary stones. It's still unclear how ureteric stones form in many ways.However, the development of minimally invasive surgeries has made ureteric calculi management much easier than in the past, with a significant decrease in morbidity.Objective:to compare the outcome of treatment of ureteric calculus by medical expulsion therapy and intravenous hydrotherapyMethods: The present study is a Comparative Analytical Study. The study was conducted in the Department of General Surgery at the Government Tertiary Care Hospital over a period of 2 years from January 2021 to December 2022. Results: The average calculus size in medical expulsive therapy was 6.51 ± 1.10mm, whereas it was 6.79 ± 1.34mm in intravenous hydrotherapy. CT urography was performed in total 66 patients and we have seen that 4 (12.12%) cases passed calculi after the medical expulsive therapy, whereas intravenous hydrotherapy shows that 21 (63.64%) cases passed calculi. After receiving medical expulsive therapy, 29 (87.87%) patients experience loin pain, compared to 9 (27.27%) patients who received intravenous hydrotherapy. There were 18 (54.55%) cases that needed to be readmitted to the hospital followed by medical expulsive therapy, whereas 12 case was readmitted after intravenous hydrotherapy.Conclusions: It can be concluded that intravenous hydrotherapy is a relatively safe and efficient treatment method in cases of ureteric calculus.