Introduction: Postpartum family planning is the initiation and use of family planning services within one-year post childbirth to prevent accidental and closely spaced pregnancies 1. Different researches have established that many postpartum women have an unmet need for contraception and that much of these unmet needs fall within the postpartum period 2. Women, their children, and the community, benefit from the use of proper family planning. This study aims to assess the knowledge, attitude and practice of family planning among postnatal mothers in a tertiary healthcare centre in South Kerala. Objectives  To assess the knowledge, attitude and practice of family planning among postnatal mothers delivering in a tertiary healthcare centre in South India.  To determine the factors influencing knowledge, attitude and practice of family planning among the subjects in a tertiary healthcare centre in South India. Methodology: A hospital based cross-sectional study was conducted among 100 postnatal mothers in postnatal OBG department wards of Dr. Somervell Memorial CSI Medical College, Karakonam, Trivandrum, Kerala. Data was collected via face-to-face interviews using a semi structured questionnaire adapted from previous studies and validated with the help of expert in the field and was pilot tested in 5% of the patients.Result: 53% of postnatal mothers had good knowledge on family planning. 93% of the study participants had a good attitude towards the use of family planning. However, a vast majority of the study participants (81%) showed poor practice. Most mothers who were graduates or had professional degree had good knowledge. So did the mothers who were working women. Spouses with good education were also seen as having a direct relationship with good knowledge score.Conclusion: Majority of the postnatal mothers (53%) have adequate knowledge regarding family planning and can be attributed to good education of mothers, education of spouse/partner and working women. It can also be derived that although the attitude towards use of family planning is good, the practice of good family planning is very poor.