Original Articles
A Randomized Comparative Study Between Hyperbaric Levobupivacaine (0.5%) And Hyperbaric Ropivacaine (0.75%) In Lower Limb Surgeries Under Spinal Anaesthesia | |
Dr. Neelam Singh, Dr. Vaibhav Tiwary, Dr. Sweta Singh, Dr. Vijayant Kumar | |
Aim: To compare efficacy of hyperbaric levobupivacaine (0.5%) and hyperbaric ropivacaine (0.75%) in lower limb surgeries under spinal anaesthesia. Material and Methods: The present study was conducted in which 80 patients of American Society of Anesthesiologists (ASA) physical status I and II, aged 18-65 years, of either sex, who were admitted to SVBP Hospital associated with LLRM Medical College, Meerut, and undergoing lower limb surgeries under spinal anesthesia were enrolled. After obtaining Institutional Ethical Committee clearance, all included patients were explained about the study, and written informed consent was taken from them. The patients were randomized and divided into two groups, GROUP R in which we administered Hyperbaric Ropivacaine (0.75%) [3ml] and GROUP L in which we administered Hyperbaric Levobupivacaine (0.5%) [3ml]. Hemodynamic monitoring devices such as a non-invasive blood pressure cuff, pulse oximeter, and electrocardiogram (ECG) were employed to monitor patients' vital signs throughout the procedure. Pain assessment tools, such as a visual analog scale (VAS) or numeric rating scale (NRS) were used to evaluate the efficacy of the analgesia provided by each drug. Results: The onset of sensory and motor block was early in group L. The duration of motor block was longer in Group L than Group R. The duration of Analgesia was longer in Group L than Group R. The hemodynamic parameters were comparable in both the groups but the SBP, DBP, MAP was on the lower side in Group L as compared to Group R. Hypotension, bradycardia, Nausea, Vomiting and Shivering were experienced by more patients in group L than group R, but no significant difference was observed. Conclusion: Hyperbaric Levobupivacaine is more efficient than Hyperbaric Ropivacaine as it has early onset of sensory block, early onset of motor block, longer duration of analgesia and longer duration of motor block. |
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