Original Articles
A Prospective Study Of Epidemiology, Clinical Presentation And Diagnosis Of Non Functioning Pituitary Adenoma In Tertiary Care Centre | |
Dr. Dharmpal Godara, Dr. Rashim Kataria, Dr. Vikas Singh, Dr. Virendra Vikram Singh Patel | |
Introduction & objectives- It is a prospective study of epidemiology, clinical presentation and diagnosis of non functioning pituitary adenoma. Their prevalence, sex ratio, age at diagnosis, age distribution and duration of symptoms were studied. The presenting manifestations, size and management of pituitary NFA has been studied. Material & methods- First 100 cases of non functioning pituitary adenoma patients admitted in department of neurosurgery from 01 august 2022 to 31 December 2023 were included in our study. All patients with pituitary macroadenomas and microadenomas (<10 mm), with or without symptoms were included. Observation & results- Visual field abnormalities and headaches were the presenting complaints in 87% and 66%, respectively. Central hypothyroidism, hypogonadism, and hypocortisolism were present in 47.2%, 35.9%, and 27.4%, respectively. Surgical resection was performed at least once in 85.7%. Conclusion- The clinical spectrum of NFPAs varies from being completely asymptomatic to causing significant hypothalamic/pituitary dysfunction and visual field compromise due to their large size. The diagnosis and treatment of NFPA are complex and require a multidisciplinary approach. |
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