Aim: The objective of this study was to analyze the clinical characteristics, management approaches, and outcomes of patients with Acute Respiratory Distress Syndrome (ARDS) admitted to the Intensive Care Unit (ICU), focusing on how ARDS severity impacts mortality, resource use, and complications. Material and Methods: This descriptive observational study included 100 patients diagnosed with ARDS in the Department of Medicine. Patients aged 13 years or older with confirmed ARDS, determined by clinical, radiological, and physiological criteria, were included. The ARDS severity was classified into mild, moderate, and severe categories based on the PaO₂/FiO₂ ratio. Exclusion criteria encompassed patients under 13 years, those who declined or later withdrew consent. Results: The cohort had a mean age of 55.20 ± 13.80 years, with a predominance of males (65.00%). Severe ARDS patients had the lowest PaO₂/FiO₂ ratios (mean 95.10 ± 12.60, p < 0.001) and higher C-reactive protein levels (p = 0.03), suggesting a stronger inflammatory response. Management included mechanical ventilation (85.00%) and prone positioning (60.00%), with more intensive interventions for severe cases. ICU mortality was significantly higher in severe ARDS (47.06%) compared to mild cases (12.12%) (p = 0.01), and severe cases had extended ICU stays and fewer ventilator-free days (p = 0.05 and p = 0.03, respectively). Complications such as sepsis and acute kidney injury were more frequent in severe ARDS. Conclusion: This study underscores the association between ARDS severity and higher mortality, prolonged ICU stays, and greater complications. Severe ARDS patients required more intensive management and had poorer outcomes, highlighting the need for early intervention and specialized care for severe cases.