Introduction: Lumbosacral radicular pain, or sciatica, represents a substantial source of discomfort, often leading to reduced mobility and significant impairment in daily activities. This condition mainly occurs because of nerve compression or inflammation in the lumbosacral area. Objective: To compare the efficacy of caudal epidural steroid injections (CESIs) with conservative treatments in alleviating lumbosacral radicular pain. Methodology: This comparative study was conducted at and a total of 55 patients diagnosed with lumbosacral radicular pain were added in the study. Patients reported radiating pain in the lower back and legs, consistent with sciatica, and had undergone diagnostic evaluations, including physical examinations, imaging studies and nerve conduction tests where necessary were included in the study. Results: Data were collected from 55 patients mean age was similar, with the CESI group averaging 52.3 years and the conservative group 50.7 years, and the gender distribution was nearly equal in both groups. BMI values were close, averaging 27.8 kg/m² in the CESI group and 26.9 kg/m² in the conservative group. The results indicate that both CESI and conservative treatments led to a reduction in pain over the 12-week period, with the CESI group experiencing significantly faster and more substantial improvements. At baseline, mean VAS scores were comparable between the CESI (8.2) and conservative (8.0) groups. Conclusion: It is concluded that Caudal Epidural Steroid Injections (CESIs) offer a more rapid and substantial reduction in pain and improvement in functional abilities compared to conservative treatments for lumbosacral radicular pain.