Original Articles
Hematologic profile in covid-19 positive patients: A retrospective study | |
Dr. Ishani Gupta, Dr. Shivani Gandhi, Dr. Reetika Menia, Dr. Jyotsna Suri | |
Background: COVID-19 is an ongoing global pandemic. Alterations in hematological profile in patients with COVID-19 are developing as significant features of the disease. A complete blood workup as well as continuous tracking of hematological parameters play a vital role in revealing the risks of disease progression and eventually help in better treatment and outcome. Objective: To co-relate the hematologic profile in covid-19 positive patients with respect to need of ICU. Methods: This retrospective study was carried out in Laboratory (Pathology Department), Government Medical college, Jammu, India. In this study, 100 patients who were confirmed as COVID-19 positive by real-time- PCR from whom a nasal swab was obtained and those who were thereafter hospitalized with an initial diagnosis of COVID-19 were studied retrospectively. Results: In the present study we have enrolled 100 patients in which 61.0% patients were male and the 44.0% patients belonging to 36-50 years age group with mean age 42.42±11.428.On comparing the laboratory parameters of the Non-ICU and ICU covid-19 positive patients it was found that WBC count, neutrophil, neutrophil to leucocyte ratio, prothrombintime, C-reactive protein and serum ferritin were was significantly higher in ICU group (p<0.05).The cutoff value of WBC count, neutrophil, neutrophil to leucocyte ratio, prothrombin time, C-reactive protein, serum ferritin, leucocyte and platelet were 6.91, 5.5, 5.81, 14.5, 59.0, 780.0, 0.73 and 1.55respectively.The accuracy of the laboratory variables were 78.4%, 91.0%, 96.7%, 86.5%, 78.7%, 83.2%, 87.0% and 77.3% respectively. Conclusion: Rapid blood tests, WBC count neutrophil, neutrophil to leucocyte ratio, prothrombin time, C - reactive protein and serum ferritin can help clinicians to assess need of ICU with COVID-19 positive patients. |
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