Original Articles
Correlation of thyroid status with severity of hypertension in pregnancy- A clinical study | |
Dr. Pallavi Agarwal, Dr. Rajan Vindochandra Kantharia, Dr. Akash Patel, Dr. Niranjan Bharti | |
Background: Hypertension, a prevalent medical disease that often raises hospitalization and death risks for both the mother and the fetus, affects about 10% of pregnant women. The present study was conducted to evaluate correlation of thyroid status with severity of hypertension in pregnancy. Materials & Methods: 70 hypertensive pregnant women were kept in group I and healthy control in group II. TSH, FT3 and FT4, severity of hypertension etc. were recorded in both groups. Results: The mean gestational age was 28.4 weeks in group I and 28.7 weeks in group II. BMI was 27.3 kg/m2 in group I and 26.2 kg/m2 in group II. SBP was 160.4 mmHg in group I and 120.4 in group I and DBP was 90.6 in group I and 76.2 in group II. The mean TSH level in group I was 4.3 µIU/ml and in group II was 2.3 µIU/ml. FT3 level was 3.1pg/ml in group I and 4.5pg/ml in group II. FT4 was 2.9 ng/dl in group I and 2.5 ng/dl in group II. The difference was significant (P< 0.05). Gestational hypertension was seen in 23, mild preeclampsia in 37 and severe preeclampsia in 10 patients. The difference was significant (P< 0.05). There was statistically significant positive correlation between systolic blood pressure (SBP) and diastolic blood pressure (DBP), as well as between SBP and thyroid stimulating hormone (TSH). There was inverse relationships between TSH and FT3, between TSH and FT4. There was no statistically significant positive relationship observed between systolic blood pressure (SBP) and free triiodothyronine (FT3), SBP and free thyroxine (FT4), diastolic blood pressure (DBP) and FT3, DBP and FT4 as well as FT3 and FT4. Conclusion: There was a strong link between pregnancy-induced hypertension and thyroid hypofunction. |
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